Studies on Oxidation and Reduction by Pneumococcus
نویسندگان
چکیده
1. The systems responsible for oxidation and reduction in the pneumococcus cell have been shown to consist of two components, the nature of which has been discussed. 2. The oxidizing and reducing power of active extracts of pneumococci is inactivated by exposure to air. This loss in activity is due to an inactivation of the thermolabile cellular component consequent on secondary reactions analogous to those which under similar conditions destroy the hemotoxin and enzymes in pneumococcus extracts.
منابع مشابه
STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS. VI. TaE OXIDATION OF ENZYMES IN STERILE EXTRACTS OF PNEUMOCOCCUS. BY JAMES
Avery and Cullen (I, 2)have demonstrated that the pneumococcus cell contains the hydrolyzing enzymes (peptonase, lipase, sucrase, amylase, inulase) and a bacteriolytic enzyme. Cole (3) (1912), (4) (1914), has shown that pneumococci also possess a hemotoxin. These enzymes and the hemotoxin are endocellular, representing actual constituents of the cell, and consequently are demonstrable in steril...
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INTRODUCTION.
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In preceding papers (1-4), the interrelations of the oxidation and reduction products of several bacterial hemotoxins were found to be analogous to the rela~ tions known to exist between the corresponding products of hemoglobin. That is, the hemolytically inactive oxidation product of the hemotoxin can be converted to the original active substance by reduction, just as "inactive" ferric hemoglo...
متن کاملStudies on Oxidation and Reduction by Pneumococcus. Iii. Reduction of Methylene Blue by Sterile Extracts of Pneumococcus
The two preceding papers of this series have dealt with the phenomenon of peroxide formation by pneumococcus. The first of these studies (1) concerned itself with the conditions under which this compound is formed when air is admitted to cultures of pneumococci which have been grown anaerobically. Under these conditions peroxide is formed at reactions and at temperatures inhibiting active cell ...
متن کاملStudies on Oxidation and Reduction by Pneumococcus. 11. the Production of Peroxide by Sterile Extracts Of
In the preceding paper (1) it was shown that pneumococci are able to form peroxide within pH zones and temperature lim its, and under other conditions, that do not permit active cell growth and multiplication. The present paper is concerned with the production of peroxide by sterile extracts prepared by freezing and thawing &e pneumococcus cell; most of these preparations were titered through B...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 41 شماره
صفحات -
تاریخ انتشار 2003